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Blood Cells and Plasma Proteins: Their State in Nature by James L. Tullis

By James L. Tullis

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Extra info for Blood Cells and Plasma Proteins: Their State in Nature

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In solutions of silver, copper, and lead acetates it is nearly as soluble as in solutions of free acid of corresponding concentration. T h e solutions made with these acetates closely resemble those made with acids. T h e positive ion enters into combination with the edestin, and no longer remains as a free ion in the solution. Acetates of zinc and mercury have no solvent action. (12, pp. 170-1) Such strong a n d specific associations obtain b e t w e e n certain metals a n d certain of t h e p l a s m a proteins t h a t complex forma4 tion must b e a s s u m e d .

091, 24 Cohn used t o illustrate t h e general phenomena. T h e solubility of t h e albumin w a s lowered t h e more, t h e higher t h e concentration of ethanol in t h e mixture; b u t t h e solvent action of t h e salt w a s greater. P l o t t e d as t h e logarithm of t h e ratio of t h e solubility O 0 6 24 Mote Fraction Ethanol 0 . 0 9 07 Molo Fraction Ethanol ( Ι β Μ. % ) ( » „ . 080 Ο 0010 0 . M 90 Mol« Fraction Ethanol ( 4 0 β· X) JL _L JL F I G . 3. Solubility of crystallized hyman serum albumin in ethanol-water mixtures at — 5°C.

3. C o h n , E . J . , M c M e e k i n , T . L . , O n c l e y , J . L . , N e w e l l , J . M . , a n d H u g h e s , W . L . , / . Am. Chem. Soc, 62, 3386 (1940). 4. D e n i s , P . , Mémoire sur le Sang. ) 11 O b s e r v a t i o n s for w h i c h w e a r e i n d e b t e d t o D r . P h i l i p W i l c o x . 42 Cohn 5. C o h n , E . J . , a n d E d s a l l , J . T . , Proteins, Amino Acids and Peptides. ) 6. C o h n , E . J . , G u r d , F . R . N . , Surgenor, D . M . , B a r n e s , Β . Α .

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