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Carotenoids and Retinoids: Molecular Aspects and Health by Lester Packer

By Lester Packer

The presence of carotenoids within the vitamin and their function in human overall healthiness has turn into a topic of unheard of curiosity. The chapters during this publication symbolize an account of the data offered at a up to date workshop, mixed with numerous extra invited contributions to hide issues extra thoroughly which are at present on the leading edge of study. the various highlights of this e-book contain a radical assessment of the detailed function that diet A consumption performs within the overall healthiness prestige of constructing international locations, the basic position of diet A in phone signaling, the molecular goals considering carotenoid motion in smoke-induced lung pathology, and the way carotenoids are precious in cardiovascular wellbeing and fitness.

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20. , and Copyright © 2005 AOCS Press Ch2Carotenoids(23-41)(Co2) 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 6/7/05 9:57 AM Page 39 Chambon, P. (1999) Cellular Retinol-Binding Protein I Is Essential for Vitamin A Homeostasis, EMBO J. 18: 4903–4914. , and Chambon, P. (2002) Analysis of the Visual Cycle in Cellular Retinol-Binding Protein Type I (CRBPI) Knockout Mice, Investig. Ophthalmol. Vis. Sci. 43: 1730–1735. , and Li, E. (2002) Increased Neonatal Mortality in Mice Lacking Cellular Retinol-Binding Protein II, J.

Evidence that vitamin A supplementation is effective in reducing child mortality in 6-mo- to 6-y-old children in high-risk populations is now available from sev5th, 50th and 95th percentiles of Serum Retinol in NHANES III Fig. 2. Serum retinol distributions by age and sex in the National Health and Nutrition Examination Survey, NHANES III, 1998–1994. Data shown are the 5th, 50th, and 95th percentiles for all individuals in the age-sex groups shown. ] Copyright © 2005 AOCS Press Ch2Carotenoids(23-41)(Co2) 6/7/05 9:57 AM Page 34 eral randomized controlled studies conducted in various regions of the developing world; several meta-analyses of these data were published [see (50,51) for reviews].

Interestingly, the survival curves began to diverge at ~2 wk of age and continued to Copyright © 2005 AOCS Press Ch2Carotenoids(23-41)(Co2) 6/7/05 9:57 AM Page 32 separate until 3 mo of age, indicating that vitamin A reduced mortality early in this period, after which the curves were parallel, indicating no further effect after 3 mo. The effect of vitamin A was greatest in low-birth-weight infants, although it could not be determined whether these were premature infants because their postmenstrual age was not known.

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