Skip to content

Current Topics in Innate Immunity by Nicole M. Lauzon, Firoz Mian, Ali A. Ashkar (auth.), John D.

By Nicole M. Lauzon, Firoz Mian, Ali A. Ashkar (auth.), John D. Lambris (eds.)

Innate Immunity has lengthy been considered as the non-specific arm of immune reaction, appearing instantly and in a prevalent method, to safeguard the host from infections. within the submit genomic period, our wisdom of the innate immune process is enriched by way of findings at the specificity of innate immune reactions in addition to to novel features that don't strictly correlate with immunological security and surveillance, immune modulation or irritation. numerous stories point out that molecules curious about innate immunity exert features which are both extra advanced than formerly inspiration, or pass way past the innate immune personality of the system.

The introduction of high-throughput systems for genome and proteome-wide profiling, including the big quantity of uncooked genetic details that has collected within the databases, have stirred new expectancies in biomedical study. they've got led scientists to revisit proven organic platforms from an international and integrative point of view. Innate Immunity study is now confronted with the problem of attempting to combine remoted biochemical pathways into complicated gene and protein regulatory circuits. during this recognize, scientists from worldwide convened on the 4th overseas convention on Innate Immunity (June four - nine, 2006), in Corfu, Greece to debate fresh advances during this quick evolving field.

This quantity represents a set of issues on normal killer cells, mast cells, phagocytes, toll like receptors, supplement, host safeguard in crops and invertebrates, evasion techniques of microorganisms, pathophysiology, protein constructions, layout of therapeutics, and experimental methods mentioned in the course of the conference.

Show description

Read or Download Current Topics in Innate Immunity PDF

Similar science (general) books

Exploring Geovisualization (International Cartographic Association)

Subtle interactive maps are more and more used to discover info - guiding us via facts landscapes to supply details and recommended perception and realizing. Geovisualization is an rising area that pulls upon disciplines similar to computing device technology, human-computer interactiondesign, cognitive sciences, graphical records, facts visualization, details visualization, geographic info technological know-how and cartography to debate, improve and review interactive cartography.

Advances in Taxation, Volume 13

"Advances in Taxation" publishes articles facing all facets of taxation. Articles can deal with tax coverage concerns at federal, nation, neighborhood, or overseas point. The sequence basically publishes empirical stories that handle compliance, machine utilization, schooling, felony, making plans, or coverage concerns.

Additional resources for Current Topics in Innate Immunity

Example text

174(2), 767-76. Kawai, T. and Akira, S. (2006) TLR signaling. Cell Death Differ. 13(5), 816-25. Lanier, L. L. (2005) NK cell recognition. Annu Rev Immunol. 23, 225-74. Lauwerys, B. , Renauld, J. C. and Houssiau, F. A. (2000) Cytokine production and killer activity of NK/T-NK cells derived with IL-2, IL-15, or the combination of IL-12 and IL-18. J Immunol. 165(4), 1847-53. Lauzon, N. , MacKenzie, R. and Ashkar, A. A. (2006) The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity.

273(20), 12203-9. Cerwenka, A. and Lanier, L. L. (2001) Natural killer cells, viruses and cancer. Nat Rev Immunol. 1(1), 41-9. Chace, J. , Hooker, N. , Mildenstein, K. , Krieg, A. M. and Cowdery, J. S. (1997) Bacterial DNAinduced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12. Clin Immunol Immunopathol. 84(2), 185-93. , Gauchat, J. , Thieblemont, N. and Delneste, Y. (2004) Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production.

1997; Lantz & Bendelac, 1994). These include the invariant NKT (iNKT) cell receptor and Vα24 independent TcRs. The iNKT cell receptor is the most studied subset of NKT cell receptors to date and is semi-invariant in nature. 2). , 2001). , 2006) will be referred to as Vα24 independent TcRs. , 2006) (see Table 1). , 2006) (see Table 2). , 2005). , 2006) have recently been reported for human NKT cell receptors, 22 Natalie A. Borg et al. Table 1. Amino acid residues composing the CDR3α loop in select iNKT and Vα24 independent (Vα24-) T cell receptors.

Download PDF sample

Rated 4.19 of 5 – based on 12 votes